Where: Washington Marriott, 1221 22nd St., N.W. Washington, DC 20037
Event URL: http://pcrm.org/resch/ara/
Fifty years after the development of the key model for the refinement, reduction, and replacement of animals in research, often referred to as the 3 Rs, The George Washington University Medical Center and the Physicians Committee for Responsible Medicine, along with the Johns Hopkins University Center for Alternatives to Animal Testing, the Institute for In Vitro Sciences, and the Kennedy Institute for Ethics at Georgetown University, invite you to Animals, Research, and Alternatives: Measuring Progress 50 Years Later. This multidisciplinary conference will bring together experts from around the world to discuss the scientific and ethical imperatives associated with animal research, changing cultural perspectives about the status of animals in society, and burgeoning alternatives to animal research. For more information about this program, click on the link above.
Where: Marriott Courtyard, Cambridge, MA, 777 Memorial Drive Cambridge, Massachusetts 02139
Event URL: http://www.invitro-models.com/
Over 60% of drugs that fail during clinical development do so for reasons of safety. The cost implications of being able to accurately predict in vivo toxicity and pharmacokinetics are huge, including:
Overall, finding problems with drugs that would only otherwise be uncovered during expensive clinical phases.
Where: Brussels
Event URL: http://ec.europa.eu/enterprise/epaa/3_events/3_3_workshops/workshop_2Rs.pdf
The objective of the workshop is to identify examples in reduction and refinement, that improve the quality of science and animal welfare, and that could be further disseminated and used more widely both within and across industry sectors. The workshop will also make recommendations on future steps to be taken towards the implementation of reduction and refinement methods and strategies that could include opportunities for research in the area of refinement and reduction and/or coordination actions (consortia) that could be supported through public and/or private financing schemes.
Where: Marriott Bethesda North Hotel and Convention Center, 5701 Marinelli Rd Rockville, MD 20852
Event URL: http://grants.nih.gov/grants/olaw/seminar/index.html
This two day symposium will celebrate and acknowledge the achievements of two and a half decades of biomedical research conducted under the U.S. Government Principles, the PHS Policy on Humane Care and Use of Laboratory Animals, and the Animal Welfare Act and Regulations. The first day of the symposium will consist of sessions focused on the advances in Animal Housing Facilities, Institutional Animal Care and Use Committees, Education and Training, and Veterinary Care. An evening session will feature a keynote address by Charles McCarthy titled “Standing on the Shoulders of Giants”. On the second day, biomedical researchers and policy experts will discuss the contributions of animal models to human and animal health.
Where: Marriott Newark International Airport Hotel, Newark International Airport, Newark, NJ 07114
Event URL: http://www.personalcarecouncil.org/2010SciSym
Join IIVS in Newark, New Jersey Wednesday October 27th and Thursday October 28th for the 2010 Science Symposium sponsored by the Personal Care Products Council. Be sure to stop by the IIVS exhibit booth to speak with some of our Study Directors and get updates on our current activities.
Where: Crowne Plaza Hotel,, 2 St. Nicholas Place Liverpool, Merseyside L3 1QW
Event URL: http://www.ivts.org.uk/pdfs/reach2010.pdf
The annual meeting of the In Vitro Toxicology Society will be held in Liverpool, UK November 2nd and 3rd.
Where: Gallaudet University, 800 Florida Ave. NE Washington , District of Columbia - 20002-3695
Event URL: http://www.alttox.org/
The Human Toxicology Project Consortium will be hosting a workshop on Accelerating Implementation of the NRC Vision for Toxicity Testing in the 21st Century, to be held November 9-10, 2010 at Gallaudet University in Washington, DC. The Consortium is a working group of several corporations, a research institute, and the Humane Society family of organizations. Further details will be posted on AltTox.org in the coming weeks.
Where: European Commission Charlemagne building, 170 Rue de la Loi (Wetstraat), BE-1049 Brussels
Event URL: http://ec.europa.eu/enterprise/epaa/3_events/ann_conf_2010/conf_2010_program_101115.pdf
Reduction and Refinement: Combining Excellence in Science and Animal Welfare
Where: EPA’s Potomac Yards South Building, First Floor Conference Room, 2777 S. Crystal Drive, Arlington, VA 22202
Event URL: http://www.epa.gov/oppfead1/cb/ppdc/testing/
Through this workshop, EPA expects to broaden and strengthen stakeholder dialogue on our Pesticide Program’s strategic vision and application of 21st Century science in the context of integrated approaches for testing and assessment to better inform chemical risk management decisions.
Where: IIVS, 30 W. Watkins Mill Road, Suite 100 Gaithersburg, MD 20878
No description provided.
Where: William H. Natcher Conference Center, National Institutes of Health Bethesda, MD, USA
Event URL: http://iccvam.niehs.nih.gov/meetings/Implement-2011/ImplmtnWksp.htm
January 19, 2011: Assessing the Potential for Chemically-Induced Eye Injuries
January 20, 2011: Assessing the Potential for Allergic Contact Dermatitis
William H. Natcher Conference Center - National Institutes of Health Bethesda, MD, USA The primary objective of these workshops is to assist participants in gaining a practical understanding of the theory and application of available alternative methods for evaluating hazard potential of chemicals and products that can also minimize animal use and avoid pain and distress. The first workshop will focus on methods for evaluating the potential for chemically-induced eye injuries, while the second workshop will focus on methods for evaluating the potential for allergic contact dermatitis. Please visit the website below for more information
Where: Berlin, Germany
Event URL: http://caat.jhsph.edu/programs/workshops/2010.63.eu.html
Implementation of the New EU Directive 2010/63/EU on the Protection of Animals Used for Scientific Purposes: Opportunities for the 3Rs.
Where: Institute for Risk Assessment Sciences, Utrecht University Utrecht NL
This course will be part of the list of supplementary courses from which the TRISK trainees can choose as their course nr 8. The course is also accessible for others interested in this issue, but admission is subject to availability of place and of the background of applicants. Applications should be sent to the course coordinator.
This course aims at providing insight into the possibilities and the limitations of the use of non-animal methods in the process of risk assessment. This includes the application of quantitative structure-activity relationships, in vitro methods, as well as their use in integrated testing strategies. It also focuses on the ethical aspects of developing and validating non-animal methods, on the methodologies used in in vitro and in silico toxicology as well as on the way in which these methods will result in another way of performing risk assessments than the classical one.
Where: Embassy Suites Washington D.C. – Convention Center, 900 10th Street Northwest Washington, DC 20001
Event URL: http://epa.nexgen.icfi.com/
In collaboration with other federal and state agencies, U.S. EPA is beginning a process to better use molecular biology to understand risks posed by environmental exposures. This transformation will occur over the next decade, and you can get involved now. Attend the 2011 Advancing the Next Generation of Risk Assessment (NexGen) Conference to learn about the program’s new ideas and provide your input.
Where: Renaissance Ballroom West A, Renaissance Hotel, 999 Ninth Street NW, Washington DC
Since 2008 CAAT has organized 3 informal meetings to further the implementation of the NRC Vision Document of Toxicity Testing for the 21st Century. Different compositions of groups have met in Baltimore, Rome and Salt Lake City. The purpose of these meetings is to inform each other about the various efforts to support setting the vision into practice.
We hope you can [again] join us, prior to the opening of the 2011 SOT meeting, to share what you have been doing in the effort to further the implementation of the NAS report on Toxicity Testing for the 21st Century. For those who want to enhance their short presentations by PowerPoint, a projector and computer will be available.
As space is limited, please register by email to: mprincip@jhsph.edu
Where: Walter E. Washington Convention Center, 801 Mount Vernon Pl NW, Washington, DC 20001
Event URL: http://www.toxicology.org/ai/meet/am2011/
Visit with IIVS staff at the 50th anniversary of SOT in Washington D.C.
The Society of Toxicology (SOT) Annual Meeting is the largest toxicology meeting and exhibition in the world, expecting to attract more than 7,000 scientists from industry, academia, and government from various countries around the globe. From the Plenary Opening Lecture and special lectures, to a wide range of Symposia Sessions to Continuing Education courses that cover the basic and the advanced topics of the day, to the workshops, thematic sessions that complement the symposia, roundtables, poster sessions, and award presentations, SOT’s Annual Meeting has something for every attendee. Confirmed plenary speakers include Dr. Francis Collins, Director of NIH and Dr. Margaret Hamburg, FDA Commissioner.
Where:
Event URL: http://caat.jhsph.edu/programs/workshops/ebt.com
A group of toxicologists with backgrounds in industry, government oversight, academia and animal welfare have created the EBT Collaboration to foster the development of a process, based on the Cochrane Collaboration in Evidence-based Medicine (EBM), for quality assurance of new toxicity tests for the assessment of safety in humans and the environment. To start the collaboration and solicit input from the stakeholder community, the EBT Collaboration steering group is organizing a workshop to take place on March 10, 2011 immediately following the Society of Toxicology Annual Meeting in Washington DC.
The kick-off meeting will introduce the participants to the concepts of the EBT Collaboration and encourage their input during the extensive discussion period. The steering committee will welcome the ideas of the audience in developing a plan for future activities. The EBT Collaboration is anticipated to be a long-range activity and be pivotal in helping to influence the development and implementation of new toxicity tests. Please visit the CAAT website for details on registration
Where: Promocell Academy, Heidelberg, Germany
Event URL: http://www.promocell-academy.com/
Topics: introduction into and applications of real-time, label- free cell assays
Where: SCK-CEN, Club-House, SCK-CEN, Club-House, Boeretang 201, B-2400 Mol, Belgium
Event URL: http://www.invitrom.org/symposium2.html
The INVITROM Working Group “Mechanisms of Toxicity” organises this symposium with the focus on the applicability of in vitro toxicity data in the risk evaluation of chemicals. An overview will be given of the current research in in vitro toxicity, which is in many cases focusing on the mechanisms of toxic action. One issue is why this increasing volume of research is not easily applicable in a risk assessment. Examples will be presented of research in integrating knowledge of toxic mechanisms in the risk evaluation of chemicals.
Where: University of Durham, Durham DH7 3LT United Kingdom
Event URL: http://www.toxicologie.nl/userfiles/File/Durham%202011%20programme_%2006_12_10%281%29.pdf
Registration: Registration will be available online at www.thebts.org. As an alternative, please contact the Conference Secretariat (contact details below). Conference Secretariat: BTS Administrative Office, PO Box 10371, Colchester, CO1 9GL, UK Tel: +44 (0)207 6852437: +44 (0)207 7 6852436 Email: meetings@thebts.org
Where: University of Rostock Department of Medical Biochemistry and Molecular Biology, University of Rostock, Schillingallee 70, 18057 Rostock, Germany Seminar room SR II, Ground floor
Real-time monitoring of cellular metabolism (bioenergetics) and cell morphology (cell impedance)
Hosted by: Prof. Dr. Markus Tiedge
Program:
10.00 Welcome - Prof. Dr. Markus Tiedge, University of Rostock
10.10 Lecture The Bionas Discovery™ cell-based analyzing systems family for continuous determination of cell physiology - Dr. Ralf Ehret, Bionas GmbH
10.55 Lecture to be announced - Prof. Stefan Wölfl, Institute of Pharmacy and Molecular Biotechnology, University of Heidelberg
11.40 Lecture Development of peptide-based cancer drugs - Dr. Jörg Andrä, Research Center Borstel - Leibniz-Center for Medicine and Biosciences
12.30 Lunch Buffet - Food for thoughts
13.40 Hands on Live presentation of the Bionas Discovery™ adcon reader “Impedance based cellular analysis in 96-well format”
Data evaluation and discussion of a running experiment
15.00 Closing remarks - Dr. Ralf Ehret, Bionas GmbH
Please email fritz.evert@bionas.de to register.
Where: The Madison Hotel, 1177 15th Street Washington, D.C.
Event URL: http://www.personalcarecouncil.org/live-meeting/2011-regulatory-science-summit
2011 marks the 4th Regulatory Science Summit that has become a very important and much needed bridge between regulators and industry. Following the highly praised format, pairing industry experts and regulators, attend sessions addressing how science policy is set, implemented and enforced; understanding the alternatives assessment under California’s proposed Safer Consumer Products Alternatives regulations (i.e., Green Chemistry initiative); as well as updates on topics of most interest to the personal care products industry.
Where: Novotel, Monte Carlo, Monaco, 16 Bld Princesse Charlotte 98000 MONACO MONACO
In vitro reconstructed human tissue models as alternatives to animal testing: applicability and limitations
Where: P&G Mason Business Center, 8700 S. Mason Montgomery Rd, Mason, OH 45040
Event URL: http://www.cermonline.com/workshops/index.htm
Sustainable Futures™ is a voluntary US EPA initiative that aims to promote the incorporation of Pollution Prevention (P2) methods through stakeholder education on the proper use and interpretation of EPA/OPPT assessment models and methods. During this workshop you will learn to use a variety of EPA/OPPT computerized models and assessment techniques to evaluate the potential hazard and exposure of a chemical substance, as well as learning how to incorporate those components into a screening-level risk assessment.
This workshop is co-sponsored by The Consortium for Environmental Risk Management (CERM) and The Procter and Gamble Company (P&G).
Where: Centro Congressi, IRCCS Fondazione Maugeri Via Maugeri, 10 – Pavia Italy
REACH is the acronym for Registration, Evaluation, Authorisation and restriction of Chemicals and it is a large-scale program for the risk assessment of all chemical substances circulating in the European Union. The aim of REACH is very ambitious and asks for a detailed (eco)toxicological characterisation of chemical substances and to the assessment of all measures that are required to manage the risks related to the handling and distribution of any chemical. The preparation of a dossier is cumbersome and needs a variety of skills embracing chemistry, toxicology, biology, etc.. REACH is a completely new program and therefore it is not backed from experienced professionals. This is the reason why Italian Universities are promoting a list of second level master courses in order to train young scientists in this field.
In parallel, the United States of America is discussing the TSCA (Toxic Substances Control Act) reauthorization, which is similar to REACH in many aspects. Moreover, the National Research Council has recently published a report titled: “Toxicity Testing in the 21st Century: A Vision and a Strategy”. This report states the limits of the traditional toxicological approach that cannot cope with the high number of chemicals as classic toxicological methods are too expensive and time consuming and sometimes their predictivity for humans is not fully reliable. A more modern and scientifically advanced approach is definitely required.
The solution may come from Integrated Testing Strategies (ITS), which are based on a combination of in vitro tests and computer modelling. The main drawback of the alternative approach and ITS is that their use is very new in the regulatory area and there is only little experience. Most of the stakeholders know very little about alternative methods and they are unaware of the opportunity of applying them, in spite of the many articles where REACH is mentioning them. Moreover, few alternative methods are validated and have the confidence of a full endorsement from regulators. However, scientific development in this field is fast and will offer surprises in the future. This state of the art is the basis for the project of promoting a lively discussion on this subject, starting from a conference addressed to all second level master students and open to all professionals that are working in this field. Among those, particular attention will be given to consultants who actively fill REACH dossiers and responsible persons from testing laboratories who may put in practice these advanced tests. Due to the scientific impact of this conference, it will be open to anybody interested in deepening knowledge on this subject.
Where: Central London UK
Event URL: http://www.nc3rs.org.uk/event.asp?id=1475
Workshop organised in collaboration with the Maths in Medicine Study Group initiative, bringing together the mathematical modelling and toxicology communities to explore the potential role mathematical modeling could play in predicting toxicity. The key aims of the workshop are to:
This workshop is open to participants by invitation only.
Where: Centro Congressi Ville Ponti , Piazza Litta, 2 - 21100 Varese
Event URL: http://ihcp.jrc.ec.europa.eu/events_workshops/dnt3conference
The meeting will be held in Varese (Italy), Centro Congressi Ville Ponti May 10-13.Developmental Neurotoxicity is an issue of growing concern in the context of chemical exposure. The developing human nervous system is susceptible to toxicants, and exposure during development may cause lasting neurological deficits. This conference, organised by the JRC, IHCP (Institute for Health and Consumer Protection), will bring together diverse stakeholders from around the globe. The following topics will be discussed: DNT and neurological deficits, DNT and regulatory legislation, Biomarkers and DNT, Gene/Environment interactions, Molecular pathways and DNT, Alternative methods for DNT Testing, Automation and potential of DNT test methods. Registration will open in November 2010. Abstract submission ends March 31, 2011. The conference will also provide an opportunity to exhibit innovative technology related to Developmental Neurotoxicity Testing (DNT) using in-vitro approaches. Potential exhibitors (e.g. manufacturers and suppliers) will be selected based on the quality and relevance of their submission to the conference themes, with preference given to those presenting innovative technology linked to cell culture techniques and various cell-based assays. Contact: JRC-IHCP-DNT3conference@ec.europa.eu
Where: Milano Convention Center, Milan Italy
Event URL: http://milano.setac.eu/?contentid=291
Ecosystem Protection in a Sustainable World: a Challenge for Science and Regulation
The SETAC Europe Annual Meeting is Europe’s biggest meeting on environmental toxicology and chemistry with more than 1500 presentations in parallel platform sessions and poster sessions, participants and scientific speakers from academia, business and government and a blend of scientists and practitioners, researchers and regulators all in attendance. The meeting opens Sunday, 15 May and ends Thursday, 19 May. We hope to see you there!
Where: Helsinki Exhibition & Convention Centre (Messukeskus), Messuaukio 1, 00521 Helsinki
Event URL: http://echa.europa.eu/news/events/6th_stakeholders_day_en.asp
The event is being planned for two consecutive days. The first is an optional day of training (17 May) and the plenary session will take place on 18 May.
The registration form and a list of speakers will be published on this page soon.
The event enables you:
* to be informed about ECHA’s activities and news
* to share views and expectations
* to receive training on REACH & CLP processes
* to ask questions
Target audience
The Stakeholders’ Day is open to all, but it is particularly relevant for those involved in REACH and CLP: industry associations, companies, public bodies, NGOs, third country representatives and the media.
Participation in the event is free of charge.
The language of the meeting is English.
Where: The Ritz Carlton San Francisco, 600 Stockton at California Street San Francisco, California 94108
Event URL: http://www.personalcarecouncil.org/legal/2011-legal-and-regulatory-conference
The Personal Care Products Council is pleased to present the 2011 Legal and Regulatory Conference on May 17-20 at the Ritz-Carlton on Nob Hill, San Francisco, California. Considered among the most important legal conference for the personal care products industry, this prestigious event is a “must attend” for those looking to stay abreast of the pressing issues facing personal care products today.
Where: Raleigh Convention Center, 500 Salisbury St. Raleigh, North Carolina
Event URL: http://www.sivb.org/meetings_aboutTheProgram.asp
Attendees of the Society for In Vitro Biology’s Annual Meeting have come to expect high quality science with opportunities for one-on-one interactions. The 2011 In Vitro Biology Meeting will offer these same opportunities and more. This year’s program includes keynote and plenary symposia, symposia, workshops, contributed papers and poster sessions. The scientific program focuses on issues pertinent to in vitro research and both animal and plant biotechnology while providing participants with a unique learning experience. This meeting attracts scientific expertise from around the globe and is an opportunity to meet and share scientific knowledge with international colleagues in a comfortable intimate setting.
Where: Crystal Gateway Marriott, 1700 Jefferson Davis Highway Arlington, VA 22202 USA Phone: +1 703 920 3230
Event URL: http://www.sustainablefragrances.com/home.aspx
Join IIVS Study Director Dr. Kimberly Norman at this years Sustainable Fragrances meeting. Kim will be on hand to talk about IIVS’ latest developments in skin sensitization and phototoxicity testing at this event. Attending Sustainable Fragrances 2011 will provide you with a thorough understanding of concepts like green chemistry, as well as insight into communications strategies, the current marketplace and the regulatory outlook. The 2011 program will give you a comprehensive look at the entire fragrance supply chain and share key insights from industry associations, companies at the forefront of innovation, government representatives and more!
Where: University of Edinburgh,
Event URL: http://www.frame.org.uk/page.php?pg_id=244
Good planning and design can have a major impact on reducing animal usage in research programs and on the welfare of the animals used. So FRAME runs regular training courses aimed at post graduate students and biomedical research scientists to teach the principles of effective experimental design and statistical analysis.
Where: Washington D. C. Area
Event URL: http://ntp.niehs.nih.gov/?objectid=26F6530D-BA27-9B29-FAE1657CB6DB907D�
The next meeting of the SACATM.
Where: Executive Conference Center (ECC), Liberty Center Arlington, VA
Event URL: http://www.sa-meetings.com/DARPA_FDAWorkshop
The goals of the workshop are: a) to introduce the biomedical and regulatory science communities to DARPA and FDA interest in modernizing regulatory science, particularly with respect to preclinical testing platforms for medical countermeasures, b) to solicit from participants ideas for technologies and/or scientific studies that promise to accelerate approval of safe and effective medical countermeasures, c) to acquaint participants with DARPA and FDA processes and programs, and d) to facilitate a dialog between the scientific/technical innovators and the FDA regarding the use of novel technologies and their potential impact on the regulatory process.
Where: City University of Hong Kong, Hong Kong
Event URL: http://www.cityu.edu.hk/bch/ista15/
The symposium provides a platform for scientists to discuss the forefront development on current issues in regulatory toxicology, “omics” technologies and bioinformatics in (eco)toxicology, toxic mechanisms of chemicals of global and emerging concerns, as well as the risk of these synthetic and natural chemicals pose on public health and environmental safety. Current advances in the fields of toxicity assessment, biomarkers and bioindicators, environmental chemistry and green chemistry, remediation and mitigation technologies will also be covered.
Where: Zurich, Switzerland
Event URL: http://www.mondialresearchgroup.com/index.php?whereTo=ratest
Animals have been kept as pets and for consumption since the beginning of time, and in most recent years for experimental purposes. Although most of the experiments performed on these animals are regarded as important for the furtherance of human and veterinary science, there is a strong movement from within the scientific community to develop methods that do not rely on animals.
Although we see many efforts in reducing animal suffering and animal experiments. It still may take a long time before we will be able to replace all animal experiments. Until such a time comes it is our responsibility to ensure every effort will be taken to reduce both the number and suffering of experimental animals.
Where: Fairmont The Queen Elizabeth , 900 René Lévesque Blvd. W Montréal, Québec Canada H3B 4A5
Event URL: http://www.wc8.ccac.ca/
Dates for the 8th World Congress have been announced. The meeting will be held August 21st through August 25th, 2011 in Montreal, Quebec, Canada.
Where: Palais des Congrès, Porte Maillot Paris, France
Event URL: http://www.eurotox2011.com/site/-Homepage,1551-
The organizing committee is pleased to announce an exciting innovative congress, with sound scientific presentations covering a wide range of topics representing the latest scientific and regulatory developments.This congress is the ideal venue for research or industry toxicologists from different regions and nationalities to meet and exchange scientific and regulatory information and knowledge. All the events, including symposia, workshops, posters and exhibition, will be held on the same level of the venue contributing in this way to these exchanges. The main subjects of the proposed meetings, workshops and roundtable discussion sessions will be detailed in the preliminary program timetable along with the names of keynote speakers and Sponsors.
Where: EDQM Premises, 7 allée Kastner 67081 Strasbourg, France
Event URL: http://www.edqm.eu/site/EDQM-Symposium-Alternatives-to-Animal-Testing-1374.html
The EDQM is pleased to announce an international symposium on alternative approaches to animal testing on 8-9 September 2011, in Strasbourg. This symposium will take a closer look at the advances being made in the development, validation and implementation of alternatives to animal testing for the quality control of biological medicinal products. In particular the progress in the fields of rabies vaccines for veterinary use, acellular pertussis vaccines, tetanus immunoglobulins and testing for pyrogens will be highlighted.
Where: TBD, Berlin, Germany
A large number of drug failures occur in the later stages of development or even after they reach the market, resulting in significant expenses for pharmaceutical companies. ADME/Tox drug failures cost companies up to $2billion annually and are driving companies to look for efficient methods of understanding toxicology. Efficiently predicting drug toxicity continues to be a major obstacle for pharmaceutical companies who want to increase productivity and reduce the risk of failure.
This 3rd annual marcus evans conference will give practitioners the opportunity to evaluate their predictive models, new technologies and internal practices to optimise the predictive toxicology strategy and improve drug candidate selection at the most affordable cost. We will provide guidance towards the ultimate aim of very early identification of compounds that are toxic to human tissue, thereby increasing the success rate of drug development while significantly reducing time to market. Attendees will receive key industry regulatory insights on data validation through to practically applying novel technologies and evaluating the cost versus standard of data from CRO’s in outsourced predictive studies.
Where: webinar,
Event URL: http://www.ascct.org
Effectopedia was conceived by the International QSAR Foundation of Duluth, MN to gather and make available sources and information on what have come to be known as Adverse Outcome Pathways (AOPs). An AOP is a description of the known linkages between molecular initiation and adverse manifestation at the organism or even population level. It is similar to, but more comprehensive than, the concept of the “toxicity pathway” described in the National Academy of Sciences report “Toxicity Testing in the 21st Century: A Vision and Strategy.”
Where: Tampere, Tampere Scandic Rosendahl Rampere Finland
Event URL: http://www.ficam.fi/images/stories/documents/28th_SSCT-Fincopa_Workshop_2011.pdf
Towards Toxicity Assessment Without Animals
We live in a chemical world. However, the safety of the chemicals to man and the risks to the environment has been studied for only a fraction of the chemical substances. The pressure to perform toxicity assessment without animals comes from various stakeholders: regulatory guidelines such as Cosmetic directive prohibit the use of animals in assessing the safety of cosmetics or cosmetic ingredients, and REACH calls for nonanimal tests to be performed when even possible, European Commission´s goal is to decrease the use of laboratory animals, industry wants cheaper and more reliable test methods than animal experiments. Today, the toxicity assessment is mostly performed with animals, but more and more robust alternative (in vitro) tests are being developed. The change from in vivo to in vitro testing has been and is being made possible by the developing science, use of human cells as well as novel tissue engineering and instrumentation solutions. The Fincopa seminar, free and open to all participants, concentrates on the status of new in vitro methods to replace/supplement animal experiments that are covered by EU-FP-7-project. The 28th SSCT workshop will start with the new updated directive of 2010/63/EU (22.09.2010) and its impact on toxicity testing strategy, followed by presentations on in vitro methods from scientific and technical perspectives. The other topics cover:
Advanced technical solutions are of utmost importance for successful cell culture work and test development. The area is developing very fast. To bring scientists up to date with new technical solutions a commercial exhibition will be organized in connection with the workshop. We are looking forward to have a meeting with up-to-date scientific knowledge. We wish you warmly welcome to Tampere and call you to send abstracts to be presented as oral presentations or as posters.
Where: Boston, MA
Event URL: http://invitro-models.com/
IIVS’s Hans Raabe will be presenting on the Neutral Red Uptake assay at this event.
“In vitro models which are predictive of the in vivo situation can save considerable time and money”.
With high rates of efficacy and safety failures in the clinic, drug developers need to ensure that improved prediction of clinical effect is achieved earlier in the drug development pipeline. But what in vitro models should you select? How do you achieve validation of a new assay or model? What candidates do you go after and screen? How have different tools performed so far and what new technologies are being developed?
These are just some of the questions that leading drug developers are asking themselves. The 2nd Predictive In Vitro Models Summit will bring together a great mix of industry leaders from pharma/biotech companies/academia to discuss how you can increase your pre-clinical predictive capability.
Where: U.S. Department of Agriculture Center for Veterinary Biologica, Ames, Iowa
Event URL: http://iccvam.niehs.nih.gov/meetings/RabiesVaccWksp-2011/RabiesVaccWksp.htm
The National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) announces an “International Workshop on Alternative Methods for Rabies Vaccine Potency Testing: State of the Science and Planning the Way Forward” on October 11-13, 2011, at the U.S. Department of Agriculture Center for Veterinary Biologics in Ames, Iowa. The workshop will be organized by NICEATM and the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM).
This workshop will bring together international scientific experts from government, industry, and academia to review the available methods and approaches that reduce, refine, and replace animals used in human and veterinary rabies vaccine potency testing, and to develop an implementation strategy to achieve global acceptance and use of these alternatives. A poster session planned for the workshop will feature presentations on current research, development, validation, and/or regulatory acceptance of alternative methods that may reduce, refine, and/or replace the use of animals in rabies vaccine potency testing.
Registration information and a workshop program will soon be available on the NICEATM-ICCVAM website. NICEATM and ICCVAM also invite the submission of abstracts for scientific posters to be displayed during this workshop; abstracts should be submitted by August 17, 2011. Online registration, instructions for poster authors, and other information will be available at the link provided.
Where: EC JRC, Institute for Health and Consumer Protection, In Vitro Methods Unit (ECVAM), Ispra, Italy
Focusing on the evaluation of potential and limitations of in silico toxicokinetic models, this workshop is a follow-up to the first EPAA workshop on this topic held in November 2008 in Dusseldorf. This workshop was successful in identifying the challenges and bringing together the relevant stakeholders. Its results have recently been published in “Toxicology in vitro”. The main objective of this 2nd workshop is to identify both scientific and methodological gaps and to generate recommendations on how to address them. It is hoped that the outcome will inform test developers, toxicologists, safety assessors, regulators and research program officers on the priorities to focus on and how to use this integrated risk assessment paradigm.
Where: Rome Italy
Event URL: http://www.celltox.it/
Organized by CELLTOX, Italian Association for In Vitro Toxicology, which will represent a special event for celebrating twenty years of activity of the Association, which will be held in Rome (Italy) from October 19-21, 2011.
The Congress Scientific program is structured into 8 Sessions, opened by a plenary lecture followed by selected oral communications and a Round Table. This congress will provide a forum for exchange of ideas and authoritative views by leading scientists; a poster session will be included to allow a direct discussion among researchers
Where: Lansdowne Resort, 44058 Woodridge Parkway Lansdowne, VA 28176
Presented by Charles River and NC3Rs.
Drug toxicologists today are caught between a rock and a hard place. The economic climate requires us to achieve more with less - more predictive safety, with less time, staff and resources. This Workshop will address this issue directly through dialog and debate in a highly interactive setting. Expert lectures will be followed by break-outs, where speakers and attendees will head for the blackboard to solve the “more with less” challenge. Prototype study designs will be used to start discussion and solicit new approaches. Traditional and new ideas will be tested against the potential to reduce animal use, “false economy” and real workplace constraints. The discussion and outcomes of the Workshop will be recorded through publication in a white paper; this is a key opportunity to contribute experience to an ongoing initiative as follow-on projects are expected.
Where: Conference-hall “NATY”, bld 34 Verhnaya st. Moscow, Russia (Belorusskaya metro station)
Scientific & practical conference is held by Russian association of cosmetic & perfumery since 1996 and now becomes the most recognizable place of cosmetic industry representatives (manufacturers, suppliers of raw materials & equipment, registration/certification bodies, testing labs) meetings in Eastern Europe.
Considering the importance of safety and efficacy of modern perfumery & cosmetics for consumers and manufacturers as well as relevancy of this topic and ongoing regulatory activities in the scope of Customs Union, the conference organizers decided to dedicate one separate day of the Conference to the topic of Alternatives as a tool of safety and efficiency assessment. This is the first time when scientific and practical background of today’s alternative methods will be discussed at this conference in Russia. In the scope of harmonization with international and European practice this information becomes very urgent and vital to set the civil practice of work on our industry. Regulatory part of the conference will be presented by competent international and local experts.
Where: Marriott Newark International Hotel, Newark Liberty International Airport 1 Hotel Road Newark, New Jersey 07114 USA
Event URL: http://www.personalcarecouncil.org/live-meeting/2011-cosmetic-science-symposium
The Personal Care Products Council 2011 Science Symposium attracts more than 250 industry leaders and decision-makers and offers personal care products industry staff one-stop shopping for information about Microbiology, Quality Assurance, Safety, and Environmental issues. With a convenient location and an information-packed program, the 2011 Science Symposium is a great opportunity to learn from the experts and meet colleagues and friends in the industry. The Symposium will also feature the Cosmetic Science EXPO enabling attendees to meet with cutting edge suppliers and technology companies to help implement the new techniques presented during the workshops. Meet up with IIVS study directors at the IIVS booth.
Where: Maritime Museum, Albert Dock Liverpool L3 4AQ United Kingdom
Event URL: http://www.regonline.co.uk/builder/site/Default.aspx?EventID=992260
IVTS members and BTS/ESTIV members please contact jeff.penny@manchester.ac.uk for a meeting discount code before registering. Full meeting registration: Delegate £210 , IVTS member £165, IVTS Student member £90, BTS/ESTIV member £185. Day rate (day 1 or day 2): Delegate £120, IVTS member £95, IVTS Student member £55, BTS/ESTIV member £105. Meeting Dinner on Tue 8 Nov 2011: £30 (option to pay during registration). Registration closes on 31 Oct 2011. Registration does not include accommodation
Where: Brussels, Belgium
“Integrated Testing Strategies (ITS) and their impact on Replacement, Reduction and Refinement Strategies”
Where: Madrid, Spain
ecopa Annual Conference
Where: Crowne Plaza Hotel Brussels Airport , Leonardo da Vincilaan Machelen, Flemish Region 1831
Event URL: http://www.sens-it-iv.eu/index.php?id=1100
As previously announced; the Sens-it-iv Consortium will organize a Congress marking the official closure of this FP6 EU funded project on November 23-25, 2011 at the Crowne Plaza Hotel in Brussels Airport. The End Congress will be preceded by the pre-meeting on T-cellsas tools in diagnostics and immunotoxicology. The objective is to actively stimulate the transfer and implementation of knowledge acquired, and tools developed, by the consortium in the areas of skin and respiratory sensitization through discussion and a market place of innovation. The objective of the pre-meeting on T-cells is to review the latest basic and applied science on T-cells as a continuation of the first Sens-it-iv-hosted T-cell meeting held in Rome Nov. 7, 2009.
The topics to be covered include:
(i) novel opportunities for test development (Scientific Spin-offs)
(ii) promising immature tests
(iii) the Sens-it-iv tool box
(iv) mechanisms of action
(v) impact of the Sens-it-iv progress on current allergy testing and regulation
(vi) gaps and future perspectives.
The targeted participants include test users, test developers, test manufacturers, regulatory authorities, scientists, and animal welfare groups.
The full preliminary program, updated on 8th of March, is available on www.sens-it-iv.eu. Registration is also possible through the website and you can find the information about the registration on the attached flyer.
The congress fee (*) is €300 private (early bird €250), €225 public (early bird €175) and €150 student (early bird €100). The fee to attend the pre-meeting is €90 for all participants. Early bird fees are valid until 31.03.2011. Rooms at the Crowne Plaza Hotel are €175/night. Please inform the congress secretariat (sensitivcongress@movistar.es) if you would like to register (early bird fees are valid until 31.03.2011) or be kept up to date with news about the congres and/or sponsoring opportunities.
Where: Utrecht University, Androclus-building, Room C101 Utrecht University Utrecht The Netherlands
Event URL: http://www.nc3rs.org.uk/event.asp?id=1712
INVITROM has organized a symposium entitled: “3D in vitro models: The real thing or an eye catcher?”
Preliminary program: (Speakers and Titles of presentations to be confirmed)
09.30 Registration and coffee
10.00 Opening and Welcome by Bas Blaauboer
10.05 - 10.40 3D Liver Model Joery de Kock (VUB, Brussels, Belgium)
10.40 - 11.15 3D Skin Model Ann van Rompay (VITO-CARDAM, Belgium)
11.15 - 11.50 3D Testis Model Aldert Piersma (RIVM, The Netherlands)
11.50 INVITROM Annual General Assembly
12.00 - 13.00 Lunch
13.00 - 13.35 3D Neurosphere Model Ellen Fritsche (IUF-Leibnitz Research Institute for Environmental Medicine, Düsseldorf, Germany)
13.35 - 14.10 3D In Vitro Disease Models Carlijn Bouten (Eindhoven University of Technology, The Netherlands)
14.10 - 14.30 Coffee Break
14.30 - 15.05 3D Bone Tissue Engineering Jacqueline Alblas (UMC, utrecht, The Netherlands)
15.05 - 15.40 To be confirmed
15.40 - Meeting Closure - Drinks
Registration:
Please use the on-line registration form.
The INVITROM symposium is free for INVITROM members. Non-members or new members: costs are 50.00 euros, including INVITROM membership for 2012. MSc students can register for a reduced fee of 25.00 euros.
Where: Research Triangle Park, North Carolina,
Event URL: http://ebtox.com/
This workshop, hosted by the multi-stakeholder EBT Collaboration, will feature sessions on validation of high throughput methods, priority areas for deploying the new methods, case studies of past and current EBT-related efforts, and governance and work processes of the EBT Collaboration as it moves forward.
Where: IIVS, 30 W Watkins Mill Rd Suite 100 Gaithersburg, MD 20878
Attend highly informative lectures given by experts in the field. Gain hands-on laboratory experience and instruction in the practical application of the lecture topics.
Topics for the 3 and a half day course include: * International regulatory acceptance status of <in vitro> assays * Predicting organ specific toxicity (e.g. ocular, dermal and hepatic) * Using cell and organ culture models with histological, biochemical and molecular endpoints * Data interpretation
This course is useful for technicians, toxicologists, managers, and directors.
Where: Washington, D.C. ,
Views are exchanged among experts from domestic and international government regulatory and health agencies, industry, academia, political policymakers, and public interest groups.Fees include gourmet luncheons and opening reception. Intimate meeting venue with abundant time for discussion and networking. In depth exploration of current topics in regulatory toxicology including human health and the environment.
Where: Marriott Marquis, San Francisco, CA,
Event URL: http://altweb.jhsph.edu/news/2012/openforum.html
This Society of Toxicology (SOT) Satellite Meeting is open to all attendees and is an opportunity for participants to provide informal updates on the work they are doing to advance the new toxicology. Participants may augment their brief presentations (5 minutes) with Powerpoint slides.
Where: Moscone Convention Center, San Francisco, CA
Event URL: http://toxicology.org/AI/MEET/AM2012/
The Society of Toxicology (SOT) 51st Annual Meeting is the largest toxicology meeting and exhibition in the world, with an expected attendance of more than 7,400 scientists from academia, government, and industry from various countries around the globe. From the Plenary Opening Lecture and featured lectures to the wide range of scientific sessions and Continuing Education courses, the Annual Meeting offers an unparalleled depth of analysis and relevant toxicological issues. From basic to advanced topical issues, the thematic approach provides each attendee an opportunity to learn about emerging fields. Whether you are speaking in or chairing a session, honoring a colleague as the recipient of an SOT award, or collaborting with your peers at an SOT event, this meeting has something for every attendee.
Where: San Diego, CA
IIVS Study Director Dr. Kimberly Norman will be giving a presentation titled “Screening Skin Sensitizers using the Novel In Vitro Skin Sensitization Assay KeratinoSens”
Where: Crowne Plaza Brussels Airport Hotel, Brussels
The desire to transition to animal-free systemic toxicity testing is fueled by testing needs such as the European REACH regulation and a possible US TSCA reauthorization as well as testing bans for cosmetic ingredients in Europe. Other areas and novel products could similarly benefit from human predictive approaches. A recent stocktaking (Adler et al. 2011) and its expert review (Hartung et al. 2011) identified gaps in the science available. In order to promote the development of a roadmap to close these gaps, an expert workshop was held (Basketter et al 2012), which shall be presented and discussed here in a multi-stakeholder forum.
Please note that the participation in this event is free of charge, and that due to the limited number of participants a registration is required. For registration please contact caat-eu@uni-konstanz.de Following the link http://bit.ly/zxAOOY you will be forwarded to the designated Hotel registration web page (the code VUB is already preset). Please click on the link above to view the agenda.
Where: The Crowne Plaza St Peters, Via Aurelia Antica, 415 - 00165 Roma
Event URL: http://www.CleaningProductsEurope.com
Network with the whole of the supply chain from raw materials suppliers to major brand owners, and all those in between. Discover new market opportunities with expert insight on regional differences in cleaning products markets and trends in emerging markets. Learn from industry leaders through insightful case studies on successful innovations. Take part in a panel discussion on approaches to innovation and building profitable business partnerships. Hear the appliance sectors perspective on achieving critical energy and water efficiency and hear the latest EU water reducing initiatives to reduce waste. At the end of a busy conference day enjoy a relaxed networking drinks reception with all other delegates and speakers and then take in the sights of the beautiful and historic city of Rome - transport into the city centre provided. The networking drinks reception is sponsored by Accelrys. Register before midnight on Monday 5th of March to save £100! Click on the link above for more information
Where: Bethesda, MD,
Event URL: http://www.personalcarecouncil.org/live-meeting/2012-regulatory-science-summit
Attend sessions addressing how science policy is set, implemented and enforced; understand the alternatives assessment under California’s proposed Safer Consumer Products Alternatives regulations (i.e., Green Chemistry initiative); as well as updates on topics of most interest to the personal care products industry.
Where:
Event URL: https://www3.gotomeeting.com/register/833531550
IIVS Study Director Greg Mun will present the basic techniques used during the performance of the Cytosensor Microphysiometer Assay. IIVS President Dr. Rodger Curren will provide information on the current regulatory status of the assay and it’s use in a tiered testing strategy. The webinar will conclude with a discussion of next generation equipment and approximately 15 minutes of question and answer time with our assay experts. There is no cost for this webinar, but space is limited. Please visit the link above to register.
Where: FDA White Oak Campus,
Co-Sponsored by the National Institute of Environmental Health Sciences, the Center for Alternatives to Animal Testing, Johns Hopkins University and the Middle Atlantic Reproduction and Teratology Association.
Registration is free but space is limited. To register, please send your name, affiliation, and email to OCSFDAWORKSHOP@fda.hhs.gov
Where: Gaiker Technology Centre premises, Parque Tecnológico, Edificio 202 48170 Zamudio (Bizkaia) (close to Bilbao) Spain
Please see the attached pdf document for the agenda of this meeting.
Where: Leeuwenberghkerk, Utrecht The Netherlands
Event URL: http://www.invitrom.org/kirkstall/kirks.html
Join us in the historic city of Utrecht for this Congress. This is a forum for Europe’s leading researchers to present their in vitro cell culture advances and exchange ideas. It is a ‘Gordon Style’ event at which everybody who attends is encouraged to contribute either by presenting papers, preparing a poster or running a discussion session. Prizes will be presented to the best student posters.
Where: Stockholm Waterfront Congress Centre, Stockholm Sweden
Event URL: http://www.eurotox2012.org/?type=static&id=23&mo=8
The EUROTOX 2012 congress will take place at the Stockholm Waterfront Congress Centre, which is centrally located in the city of Stockholm with accommodation, restaurants, pubs, coffee shops, theatres etc all within walking distance.
The scientific programme will be designed with input from toxicologists of all parts of Europe and in line with the cutting edge of toxicology and safety science. There will be poster sessions and a continuing education programme.
The meeting will offer plenty of opportunities for discussions and interactions between the participants and celebrate 50 years of toxicology organisations in Europe.
The attractive social programme includes a welcome reception, a congress dinner and a reception.
For those who want to take the opportunity to enjoy Stockholm, Sweden and the rest of the North before or after the congress, there will be ample opportunities to do so.
Where: Tallinn, Estonia,
Event URL: http://qsar2012.ut.ee/
The workshop has become an important international gathering in the fields of Environmental and Health Sciences, bringing together people developing and using (Q)SAR-s to explain the behavior of chemicals in nature and living organisms. The Workshop has attained great recognition as a forum that helps to build common understanding and solutions in explaining the influence of chemical structure on various physical, chemical, biological, and health endpoints, as well as in understanding systems chemistry and, at the end of the line, contributes to the improvement of quality of life.
Where: Dübendorf, Switzerland,
Event URL: http://www.euroecotox.eu/
EUROECOTOX is an European Network that aims to contribute to the advancement of alternative methods of ecotoxicity testing in Europe and promotion of the validation and regulatory acceptance of new alternative methods in ecotoxicology. One activity of the network is the organization a forum with keynote speakers and talks/posters selected from abstract submissions. The conference will be a platform for young scientists and experts from academia, industry and regulation in the research field of 3Rs within environmental risk assessment. The focus will be on the current state and future directions of the development, implementation and application of the 3Rs, from bench to acceptance.
Where: U.S. Department of Agriculture Center for Veterinary Biologics at the National Centers for Animal Health, Ames, Iowa
Event URL: http://iccvam.niehs.nih.gov/meetings/LeptoVaccWksp-2012/LeptoVaccWksp.htm
The National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) announces an “International Workshop on Alternative Methods for Leptospira Vaccine Potency Testing: State of the Science and Planning the Way Forward” on September 19-21, 2012. The workshop will be hosted by the U.S. Department of Agriculture Center for Veterinary Biologics at the National Centers for Animal Health in Ames, Iowa. NICEATM is organizing the workshop in collaboration with the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) and partner organizations in the International Cooperation on Alternative Test Methods.
This workshop will bring together international scientific experts from government, industry, and academia to review available methods and approaches that can reduce, refine (enhance animal well-being and decrease or eliminate pain and distress), and/or replace animal use for veterinary Leptospira vaccine potency testing, and to develop an implementation strategy to achieve global acceptance and use of available alternatives. A poster session will feature presentations on current research, development, and validation of alternative methods for Leptospira vaccine potency testing.
Leptospirosis is an emerging and widespread bacterial zoonotic disease caused by spirochetes of the genus Leptospira. Worldwide more than 500,000 human cases of leptospirosis are reported each year with a fatality rate of up to 25% in some regions. Designated as a Neglected Tropical Disease by the National Institutes of Health and the World Health Organization, leptospirosis is a global research and public health priority. Leptospirosis also affects many animal species including livestock, pets, and wildlife. In the United States, vaccines are used to protect cattle, swine, and dogs, and human vaccines are available in some other countries. Regulatory authorities require potency testing prior to release of each production lot of Leptospira vaccine to ensure that it will be effective. However, such testing currently involves large numbers of laboratory animals. Many animals experience significant unrelieved pain and distress, accounting for over one-third of the animals reported to the USDA in this pain category. Accordingly, NICEATM, ICCVAM, and its international partners recently identified Leptospira vaccines as one of its top three priorities for development, validation, and implementation of improved alternatives.
The upcoming workshop will review recent advances in science and technology and new methods and approaches that are more humane, that use fewer or no animals, and that may provide improved accuracy, efficiency, and worker safety. The workshop will also address global acceptance and implementation of scientifically valid alternative methods. Registration information and a workshop program will soon be available on the NICEATM-ICCVAM website. NICEATM and ICCVAM also invite the submission of abstracts for scientific posters to be displayed during this workshop; abstracts should be submitted by August 13, 2012. Online registration, instructions for poster authors, and other information will be available at the link above. If you have questions about the workshop or would like more information, please contact NICEATM at niceatm@niehs.nih.gov.