Listed below are the latest publications added to IIVS’ online document library. To search our library, please visit our Resources page.
Digital Dispensing onto 3D Airway Tissue: Delivery of Patterned, Picoliter Volumes for Direct Apical Surface Coverage with Precise Quantities of Test Material
The availability of human reconstructed airway tissues presents researchers with a platform that more closely resembles airways in vivo. Grown at the air-liquid interface (ALI), these tissues offer apical and basal compartments that allow flexibility in modeling physiologically relevant exposures, but also allows sampling location-specific quantitation of biological responses.
Evaluation of New Solvents for the Use in the Multi-Dose Reconstructed Human Epidermis (RhE) Phototoxicity Assay
Effect of Acclimation Conditions on 3D Human In Vitro ALI Airway Models: Exposure-Induced Inflammatory Response and Sampling Location-Specific Results
Correlation of Two In Vitro EpiOcular Test Methods and Consumer Eye Irritation Data for Cleaning Products
Combining in silico and in vitro Methods to Improve the Accuracy of Skin Sensitization Predictions for Chemicals
2014 TSRC: The Use of Precision-cut Lung Slices to Assess Inflammation, Parenchymal Damage, and Collagen Deposition: Three Markers of Tobacco Exposure-induced Pulmonary Toxicity
This first-of-its-kind respiratory toxicology workshop was attended by more than 60 participants of diverse backgrounds, including FDA-CTP attendees and an FDA-CTP speaker. 12/2014
2014 CORESTA: Toxic Insult to Rat Precision Cut Lung Slices Increases Tissue Cytokine Levels and Activation of Macrophages, and Causes Acute Damage, While Prolonged Insult May Lead to Increased Deposition of Collagen - a Marker of Fibrosis
2014 IIVS Workshop: Assessment of In Vitro COPD Models for Tobacco Regulatory Science Overview: Etiology of COPD and In Vitro Models
2014 IIVS Workshop: Assessment of In Vitro COPD Models for Tobacco Regulatory Science Detection of Inflammation and Parenchymal Damage Using Precision-cut Lung Slices