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The Organisation for Economic Co-operation and Development (OECD) has officially adopted two test guidelines for identification of substances with the potential to cause eye injury. One of these (OECD TG 405), an updated test guideline for the traditional rabbit eye test, incorporates specific procedures to avoid or minimize animal pain and distress when it necessary to use animals to identify substances with the potential to cause eye injuries. The other test guideline (OECD TG 460)provides a new method to identify substances that may cause serious eye injuries without using animals. Both guidelines, along with all of the current OECD test guidelines for the testing of chemicals) can be viewed on the OECD website by clicking on the link above.