Forsby, Norman et al. Article on Eye Sting Editor's Highlight in the Current Issue of Toxicological Sciences
The paper chosen for the Editor's Highlight in the October 2012, Vol. 129, No. 2 issue of Toxicological Sciences is "Using Novel In Vitro NociOcular Assay Based on TRPV1 Channel Activation for Prediction of Eye Sting Potential of Baby Shampoos" by Anna Forsby, Kimberly G. Norman, Johanna EL Andaloussi-Lilja, Jessica Lundqvist, Vincent Walczak, Rodger Curren, Katharine Martin, and Neena K. Tierney.
Editor, Michael L. Cunningham notes that "Replacing animal testing for pain induction by chemicals is a goal of animal welfare research. Forsby et al. make a significant advancement in this field by the development of the NociOccular test for baby bath and shampoo formulations. This assay is a recombinate neuronal in vitro model of activation of the Transient Receptor Potential Vanilloid type 1 channel, a well characterized pain-inducing receptor. This research opens the way for the development of future assays to predict pain induction without the use of animals."