The National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) in collaboration with the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) has developed a draft updated NICEATMICCVAM Five-Year Plan. This document will provide strategic direction for NICEATM and ICCVAM during 2013 to 2017. It outlines how, consistent with ICCVAM's statutory duties and purposes, NICEATM and ICCVAM will contribute to the transformation of safety testing by fostering and promoting the incorporation of scientific advances and innovative technologies into new improved test methods and integrated testing and decision strategies. As announced in the Federal Register, NICEATM and the National Institute of Environmental Health Sciences (NIEHS) request public comments on the draft 2013-2017 Five-Year Plan, which is available on the NICEATMICCVAM website at the link above. Comments are requested by August 13, 2012 and may be submitted online.